International Narcotics Control Strategy Report

The 2025 International Narcotics Control Strategy Report highlights both progress and growing global challenges in combating illicit drug trafficking. While U.S. overdose deaths declined for the first time in years, synthetic opioids—especially fentanyl—remain the primary threat, with China and Mexico key sources of precursor chemicals and trafficking routes. International cooperation surged, including expanded partnerships and commitments through a global coalition to disrupt synthetic drug supply chains. Still, countries like Burma, Venezuela, and Bolivia were flagged for failing to meet drug control standards, underscoring the urgent need for sustained enforcement, accountability, and public health interventions.