This executive order formally designates illicit fentanyl and its core precursor chemicals as Weapons of Mass Destruction, recognizing the scale of harm and national security risk they pose. It outlines coordinated actions across federal agencies to disrupt trafficking networks, strengthen prosecutions, and target the financial systems that enable distribution. The order also expands how the U.S. government prepares for and responds to chemical threats linked to fentanyl. Together, these measures reflect a shift in how synthetic opioids are treated within national defense and counterterrorism frameworks.

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| Website: | Visit Publisher Website |
| Publisher: | The White House |
| Published: | December 15, 2025 |
| License: | Public Domain |